The Newton family live in their comfortable home, but there seems to something missing. This "hole" is filled by a small puppy, who walks into their home and their lives. Beethoven, as he is named, grows into a giant of a dog... a St Bernard. Doctor Varnick, the local vet has a secret and horrible sideline, which requires lots of dogs for experiments. Beethoven is on the bad doctor's list.
Charles Grodin, Bonnie Hunt, Dean Jones, Nicholle Tom, Christopher Castile, Sarah Rose Karr, Oliver Platt, Stanley Tucci, David Duchovny, Patricia Heaton, Laurel Cronin, O-Lan Jones, Nancy Fish, Craig Pinkard, Robi Davidson