Up to a house high on a mountain top have been invited ten people who are strangers to each other. When they are all gathered, they hear from their host that each one of them has in someway caused the death of an innocent person and that justice had not be served in their cases. There are eight guests and two servants there for the weekend, but one by one, they are being knocked off according to the poem of "Ten Little Indians". As the number of survivors decreases, they begin to believe that the killer is one of the group, but are unable to decide on which one he or she may be.
Hugh O'Brian, Shirley Eaton, Fabian, Leo Genn, Stanley Holloway, Wilfrid Hyde-White, Daliah Lavi, Dennis Price, Marianne Hoppe, Mario Adorf, Bill Mitchell